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The treatment-policy estimand is closer to intention-to-treat: it estimates the effect regardless of whether participants stayed on treatment or used rescue therapies

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Commenters' request to exclude the proposed transitional payment exception from budget neutrality is inconsistent with the budget neutral requirement under 1833(t)(2)(D) of the Act

You are considered vitamin D3 deficient with levels below 30, and sub-optimal between 40-60

These details separate good protocols from excellent ones