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The antibody simtuzumab, targeting extracellular LOXL2, has undergone clinical trials in combination with gemcitabine for patients with metastatic pancreatic adenocarcinoma or with FOLFIRI (folinic acid, fluorouracil, and irinotecan) for patients with KRAS mutant colorectal cancer [102, 103]

Semaglutide has clinical evidence supporting its effectiveness for weight loss and diabetes management

This follows US Health and Human Services Secretary Robert F

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