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An excess of Fe 2+ leads to the production of ROS through the Fenton reaction, which induces cell damage or death and potentially impairs organ function eventually

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Usually normal Small red bump or raised area at the site Mild itching that fades within hours Minor bruising from the needle Brief stinging or pinching during injection Contact your provider Spreading redness or warmth around the site Pus or discharge from the injection point Swelling that worsens after 24 hours Signs of allergic reaction: hives, swelling away from site, difficulty breathing Rotating sites each week and using correct technique reduce local reaction frequency