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42) In SUSTAIN-6, patients treated with semaglutide had a lower risk of developing or worsening nephropathy, but a higher risk of complications from diabetic retinopathy than those receiving placebo (40)

These potential biological effects remain under investigation in experimental research and should not be interpreted as established therapeutic outcomes

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Adjust medication if necessary 3

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Why Slow Dose Titration Prevents GLP-1 Overdose Risk Pharmaceutical guidelines recommend starting semaglutide at 0.25 mg weekly, increasing by 0.25 mg every four weeks until reaching a therapeutic dosetypically 1.02.4 mg weekly