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Rather than engaging a single high-affinity receptor, the pentadecapeptide modulates multiple intersecting cellular pathways including nitric oxide system signalling, growth-factor receptor expression (notably VEGF receptor 2 and growth-hormone receptor), dopamine and serotonin pathway markers, and angiogenic factor regulation

It stimulates fibroblast proliferationthe cells that produce your extracellular matrix and structural proteins

Lipid Profile -30% cholesterol Significant reduction in total plasma cholesterol (p 30%) and white adipose tissue volume (-35%)

Acknowledgements Simin Zhang, Mei Han, and Shan Li contributed equally to this work

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