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Description

It says GLP-1 drugs enhance secretion of intestinal hormones partly through intact bile acid signaling, so a shifted signaling environment can change efficacy, gastrointestinal side effects and metabolic response

2015;(9):CD004069

Physicians typically recommend GLP-1 therapy in teens only after intensive lifestyle intervention has been attempted and metabolic comorbidities (such as type 2 diabetes or severe hypertension) are present