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Mass Spectrometry Validates molecular identity and correct sequence

(1993) Rapid pressure driven exocytosis-endocytosis cycle in a single plant cell FEBS Lett., 333, 283-286 12

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Importantly, nuclear-localized FOXO4-positive Leydig cells in elderly testes showed reduced expression of 3-HSD, a rate-limiting enzyme in testosterone synthesis, implying a connection between nuclear FOXO4 and age-related decline in testosterone production [1]