Despite considerable focus on intracellular GSH synthesis and membrane transport 29,30 , the mechanisms governing mitochondrial GSH import remain poorly understood
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Wang MH, Friton JJ, Rebert N, Monroe K, Nix BD, Fiocchi C, et al
Excipient studies on lyophilized rhGH show that sugar and polyol stabilizers (mannitol, sucrose, trehalose) protect the protein's secondary structure and limit aggregation in the dry state by satisfying water-binding sites and stabilizing the amorphous matrix around the protein (Costantino et al., 1998)