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This dual agonism allows it to amplify the benefits of each hormone, resulting in superior metabolic effects

SS-31 targets mitochondrial cardiolipin, improving cellular energy production and reducing oxidative stress at the cellular level

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As IBD involves oxidative stress and inflammation, these diverse antioxidants collectively act as a shield against cellular damage, offering a multifaceted approach to treatment

Therefore, diabetic wound healing can be accelerated by promoting epidermal formation, collagen deposition, and neoangiogenesis

Then, the inhibition of HIF1A further suppressing the expression of FABP3 (fatty acid binding 3) and FABP7, which ultimately promoting the occurrence of lipid peroxidation and ferroptosis [212]