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Substantial liver damage can occur before any warning signs like nausea, dark urine, or jaundice become apparent

Loguercio, C., et al

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Research demonstrates that tyrosine supplementation supports healthy cognitive function under conditions of physiological stress, cold exposure, or cognitive overload when endogenous catecholamine stores become depleted faster than they can be replenished through normal dietary intake

ALA may cause hypoglycaemia in diabetics, and CoQ10 may reduce warfarin effectiveness, requiring closer INR monitoring

doi:10.1007/s12011-011-9278-4