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Mechanisms of disease: role of chondrocytes in the pathogenesis of osteoarthritisstructure, chaos and senescence

Even though targeting Nrf2 has been demonstrated to exert anti-ferroptosis effects in the context of cancer cells, there is still insufficient evidence in the field of neurodegenerative disease therapy, and the specific markers, genetic regulation, and other studies have not been clear

In addition to inducing apoptosis, the transfer of HMGB1 from the melanocyte nucleus to the cytosol under oxidative stress can also suppress Nrf2 expression [52, 53]

Conflicts of interest The authors declare no conflict of interest

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The resulting fluorescence spectrum was notable for its distinct vibrational structure and a maximum emission ( max ) at an unusually short wavelength of 308 nm (Burstein et al., 1977)