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1.0 mg semaglutide (dose escalation from 0.25, to 0.5, and then to 1.0 mg) or placebo for 52 weeks [100]
To exclude the loss of components during the fractionation procedure, the solute and eluate of CAF-CM were re-pooled together and tested
Research demonstrated that the pentadecapeptide promotes tendon fibroblast outgrowth, cell survival, and cell migration in tendon explant models providing a mechanistic basis for the musculoskeletal-repair findings widely reported in the preclinical literature 4
10.1016/j.pharmthera.2018.04.007 118
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