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& Mardesic, S

Some of the more common side effects include: Nausea and vomiting Abdominal pain and bloating Indigestion or acid reflux (heartburn) Constipation or diarrhea Weakness during exercise Headache Although they can be unpleasant, these effects are generally not dangerous and can be reduced through small adjustments to our lifestyle

The drugs appear to induce weight loss by delaying the emptying of the stomach, making people feel fuller for longer, and reducing cravings for food as well

The Weill Cornell cohort study (255 GLP-1RA subjects, 92% women, mean age 64) found that greater annualized hip bone loss was concentrated in patients without diabetes - exactly the demographic of postmenopausal women using GLP-1s purely for weight management

It's a formidable, often-unseen barrier to progress

All these things are costly and are covered my Employers and Plan Sponsors, downstream from the obesity