R169Q, R169P and R169W are all variants associated with SPCD 11 , all of which we hypothesise affect the positioning of both D165 and E220, and subsequently the gating interaction between R459 and E220
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vomiting (8% vs 7%)
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Ann N Y Acad Sci (2010) 1199:5268
Exploring peptide-based compounds in scientific research has increased interest in synthetic analogs that may impact physiological processes