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Between screening and randomization, across all groups, mean systolic BP decreased by 5.711.0 mm Hg, diastolic BP by 3.78.1 mm Hg and pulse rate fell by 0.910.1 beats min 1

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30 A total of 711 patients with T2DM (mean baseline A1C of approximately 8% in all treatment groups) were enrolled and randomized to receive one of three interventions: 1) 14 mg daily of oral semaglutide

Metformin reduces glucose production in the liver and improves insulin sensitivity

This mechanism supports the use of oral NAC as a defence against neuronal oxidative stress and maintaining redox balance

Rosenthal SB