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Current Opinion in Neurobiology, 4(5), 696-702.
Nature 453 , 783787 (2008)
Eligibility and dosing The tablet is licensed for adults with obesity, with a body mass index (BMI) of 30 or above, or those who are overweight with a BMI between 27 and 30 with at least one weight-related comorbidity, alongside a reduced-calorie diet and increased physical activity
These immunomodulatory properties may enhance the effectiveness of conventional biologic therapies and could potentially support disease control in early PsA, although this possibility still requires confirmation in dedicated clinical studies, a phase in which immune dysregulation is still evolving
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