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EMA recommends annual cardiovascular evaluation due to possible long-term risks

Brooks AJ, Vlasie M, Banerjee R, Brunold TC

Steroids raise your blood glucose levels in the following ways: They block the action of insulin which causes insulin resistance Less glucose is taken up by the muscles from the bloodstream They cause the liver to start releasing extra glucose into the bloodstream Steroids are available in different forms Tablets (oral steroids) Injections which can be into blood vessels, joints or muscles Inhalers such as mouth or nasal sprays Lotions, gels or creams (topical steroids) Inhaled steroids used for asthma do not affect blood glucose levels

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General Implications for Oral Medications: For medications where rapid onset of action is critical, or for those with narrow therapeutic windows, the delayed gastric emptying caused by tirzepatide warrants careful consideration

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