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Age-Related Considerations: The primary effect of appetite suppression and weight control is observed in both adults and pediatric patients

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These include sensitivity to azole drugs in response to disrupting UPC2 ( CPAR2_207280 ) 19,36 or the ATPase encoding gene ISW2 ( CPAR2_404600 ) 37 , hypersensitivity to hydrogen peroxide in SKN7 ( CPAR2_304240 ) disruptions 37 , to oxidative stress and cadmium in CAP1 ( CPAR2_405030 ) disruptions 38,39 , and to osmotic stress response and oxidative stress in disruptions of the MAPK kinase PBS2 ( CPAR2_806570 ) 40 (Fig