Because the peptide occurs naturally in human plasma (at roughly 200 ng/mL in young adults, declining to approximately 80 ng/mL by age 60), topical supplementation essentially restores youthful local concentrations in treated skin
3 During these trials, which investigated the utility of these drugs for glycemic control, GLP-1RAs showed a secondary benefit of weight reduction, which has led to their recent approval for weight management in several countries worldwide
This perspective helps ensure that treatment decisions are made based on comprehensive health goals rather than single outcomes
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The ProMPT study was supported by the UK NIHR, Cancer Research UK and the MRC, and the Cambridge and Oxford Biomedical Research Centres
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