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control, 194) showed no significant effect of NAC supplementation on SHGB levels (WMD: 168 nmol/l, 95 % CI (210, 545), P = 0383) (online Supplementary Fig

Importantly, while the effects of ammonia exposure on the GM can be caused both by direct exposure, it can also stem from the acidification resulting from hydration to ammonium

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Its therefore essential to investigate how these medicines perform in everyday clinical settings. Reference: Pasternak, N., et al