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486 The temporal selectivity of this probe was improved in a subsequent study wherein it was caged at the 1-position with an N ,N -diacetyl-l-lysine group, via a self-immolating p -aminobenzyl alcohol linker, making it activatable by histone deacetylase (HDAC) enzymes and thus selective to labeling of cancer cells that bear high HDAC activity (Figure 70)