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Furthermore, epithelial cells are held together by tight junctions (TJs) and adherens junctions (AJs), both essential for maintaining epithelial barrier integrity

Combined treatment with IGF-IR inhibitor, PARP inhibitor, and/or platinum may be a strategy to improve the efficacy of cancer therapy [100]

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Andrew: -by the FDA

Tingling or flushing with very high doses of B3 or B6 (uncommon in clinical settings with proper dosing)