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[DOI] [PMC free article] [PubMed] [Google Scholar] 69.Mller T.D., Finan B., Bloom S.R., DAlessio D., Drucker D.J., Flatt P.R., Fritsche A., Gribble F., Grill H.J., Habener J.F., et al

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The shared biological properties of exendin-4 and human GLP-1 probably stem from their primary and secondary structures, but exendin-4 is naturally resistant to degradation by the DPP-4 enzyme, attributed to the presence of glycine at position 2, resulting in an intravenous half-life of approximately 30 minutes (85)

Huynh, A

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Nature 477 , 549555 (2011) Deupi, X