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During the acute phase of the virus, the immune system launches a massive inflammatory response, generating enormous amounts of reactive oxygen species (ROS) to destroy the invading pathogen

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The stabilization and nuclear translocation of Nrf2 result in the transcription of antioxidant response element-regulated genes such as HO-1, NQO1, GCLC, SOD, catalase, and GPx, which together enhance glutathione synthesis, maintain mitochondrial redox balance, suppress lipid peroxidation, and improve cellular resilience to oxidative insults

Glycolysis differentially regulates K l-la , K d-la and K ce K l-la , K d-la and K ce are all formed from precursors that are intermediates in glycolysis (Fig

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