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In pediatrics, most available studies do not stratify outcomes by sex, underscoring an important knowledge gap and the urgent need for research that addresses sex-specific responses during childhood and adolescence

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Studies have explored growth hormone receptor upregulation and VEGF pathway activation as potential mechanisms that could explain this multi-tissue activity though the complete mechanistic picture remains an active area of investigation

Asimismo induce una reduccin ponderal semejante los AR GLP-1 de accin prolongada, a travs de un efecto directo inhibidor del apetito(14)

Individual patient factors play a significant role as well