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Notably, the majority of checkpoint-oriented AD models still lack measurement of ferroptosis-defining hallmarks or validation using ferroptosis-selective rescue paradigms (see Table 2)

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1 2 3 4 5 6 7 8 "Resistance is not futile: Gliotoxin biosynthesis, functionality and utility" (PDF)

doi: 10.1038/nchembio.1416 31

And that makes it hard on the rest of the body to carry oxygen and nutrients through circulation in a normal manner