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Chronic inflammation has been linked to depression, so this is an important factor

The idea of "getting your money's worth" can cause people to eat beyond their comfort level

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If you're also experiencing increased hunger or fatigue, these are signals that your dose may be too low, your caloric deficit is unsustainable, or you need structured nutrition coaching to break the plateau

Sui M, Jia X, Yu C, Guo X, Liu X, Ji Y, Mu S, Wu H, Xie R (2014) Relationship between hypoalbuminemia, hyperlipidemia and renal severity in patients with lupus nephritis: a prospective study