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[12] [21] Insulin remains the gold standard for diabetes management when oral agents are insufficient

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For patients seeking deeper insight into their individual response to GLP-1 therapy, the PlexusDx Precision Peptide Genetic Test ($99 add-on after your first month) analyzes 14 metabolic pathways and 49 peptides, including genetic variants in GLP1R (rs6923761), MC4R (rs17782313), and other receptors that influence both weight-loss response and side-effect sensitivity

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