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These mitochondrial morphological changes may be related to high gene expression and the ability to stimulate the activity of the P53 tumor suppressor protein (Teulings et al., 2013) and SOD enzymes (Laddha et al., 2013)

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10.3390/medicina60101647 110 SongD.SongJ.WangC.LiY.DunaiefJ

SIRT1 exhibits broad expression across intestinal epithelial cells, including the colon and small intestine, especially in the crypt region (Wellman et al., 2017)

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