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Recently, to ensure the safety of GLP-1 RA on sarcopenia, a clinical randomized multicenter trial of bimagrumab, an antibody blockade of activin type II receptor inhibitor, alone or in addition to subcutaneous semaglutide is now ongoing (NCT05616013) [113]

De nyare lkemedelsklasserna SGLT2-hmmare, som empagliflozin, och GLP1-agonister, som semaglutid, har ftt stor betydelse i behandlingen av typ 2-diabetes d studier visar att de skyddar patienterna frn kardiovaskulra komplikationer.

Mol Metab 2021;46:101102.PubMed 3

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Tirzepatide (Mounjaro, Zepbound) is a dual GIP/GLP-1 receptor agonist that works through similar mechanisms