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Complementary findings in dietary obesity models have also been reported, where AgRP levels were elevated under hyperphagic conditions and reduced with food restriction, while -MSH and POMC concentrations remained unchanged [60]

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Evidence suggests shedding is secondary to weight loss and nutritional shifts rather than direct follicular toxicity

Some participants discontinued treatment due to side effects, particularly at higher doses, a reminder that individual tolerance and clinical monitoring are important considerations in any metabolic intervention

This concentration is great for studies requiring larger doses, as it keeps the injection volume small