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[24] Role in cell signaling [edit] Although best known for their ability to conjugate xenobiotics to GSH and thereby detoxify cellular environments, GSTs are also capable of binding nonsubstrate ligands, with important cell signaling implications

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Hormones like estrogen and progesterone stimulate melanocytes, leading to dark patches on sun-exposed areas, especially during pregnancy or with birth control

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Secondary endpoints showed improvements in waist circumference (13.5cm), HbA1c (0.45%), and cardiometabolic risk markers

The trials look to find new ways to prevent, detect, or treat disease and improve quality of life