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In another set of experiments, cells were preincubated with 10 M LY294002 for 30 min at 37 C and then stimulated with bTNF- for 5 min

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Safety, tolerability, pharmacokinetics, and pharmacodynamics of concomitant administration of multiple doses of cagrilintide with semaglutide 24 mg for weight management: a randomised, controlled, phase 1b trial. Lancet 397(10286):17361748