The suggested mechanism for the increased risk is the higher incidence of diarrhea and dehydration experienced while taking the drug, leading to increased blood viscosity
The result is a frustrating cycle of initial weight loss followed by plateaus and eventual regain
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[1] The medication works through dual agonism of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors, which helps regulate appetite and reduce food intake