The brain, due to its high metabolic activity, is especially susceptible to oxidative stress, and its natural defense mechanisms, like antioxidant enzyme systems, are often inadequate in these diseases
It plays a role in cellular metabolism
Apolipoprotein E4 effects in Alzheimer's disease are mediated by synaptotoxic oligomeric amyloid-
In relation to the primary site of infection, Ab treatment modulated the inflammatory response into peritoneal cavity of septic mice, inducing almost complete bacterial burden elimination 24 h post CLP and a significant augment in NO levels, without alterations in IL-1 and TNF- levels in relation to CLP-saline treated mice
the enzymes in your skin called esterases gradually convert it into active vitamin E over time
New England Journal of Medicine 367, 17921802 (2012)