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Patients should be advised to contact their GP or diabetes care team promptly if they experience any of the following: Emergency (999/A&E attendance): Urgent referral indicators (same-day assessment to multidisciplinary foot care service): Ulceration or breaks in skin integrity (any suspected diabetic foot ulcer) Signs of infection : warmth, redness, swelling, discharge, or systemic symptoms (fever, malaise) Severe pain , particularly if sudden in onset or associated with colour changes Suspected acute Charcot foot : red, hot, swollen foot, often with minimal pain in the presence of neuropathy Ischaemic signs : cold feet, absent pulses, pallor, or pain at rest Unilateral, painful swelling (possible deep vein thrombosis) Routine review appropriate for: Persistent foot pain or discomfort affecting mobility or quality of life Gradual onset of tingling or altered sensation Bilateral, mild swelling that resolves with elevation Concerns about foot shape changes or difficulty finding appropriate footwear Development of calluses, corns, or areas of pressure Patients with established diabetic neuropathy or peripheral arterial disease should have enhanced surveillance and may require referral to specialist podiatry or multidisciplinary diabetic foot services, in line with NICE NG19 recommendations

Slower digestion supports healthier eating patterns and better awareness of fullness cues
The idea behind pairing CJC1295/Ipamorelin with smart nutrition and movement is to support muscle and recovery while fat comes down
Fast responders, comprising another 30-40% of users, experience meaningful improvement within the first 1-2 weeks
Severe cases of gastroparesis can also disrupt intestinal motility throughout the gastrointestinal tract, potentially contributing to constipation, bowel obstruction, or impaired movement of waste into the large intestine