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However, the design of SURPASS-4 was based on the change in HbA 1c at 52 weeks, and not on MACE, as the primary outcome [21]

Lund JN, Armitage NC, Scholefield JH

Theres no clinical requirement to escalate on the fastest possible schedule

doi:10.1093/cid/ciu065 Dinleyici EC, Eren M, Dogan N, Reyhanioglu S, Yargic ZA, Vandenplas Y

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