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It adds that providers should assess both tolerance and metabolic response before any increase, so tolerability and pace are linked rather than independent
Chen, J.N., Orkin, S.H., Kurdistani, S.K., Evans, S.M., Nakano, A., Mikkola, H.K., "Scl Represses Cardiomyogenesis in Prospective Hemogenic Endothelium and Endocardium", Cell 150: 590-605 (2012)
Ive tried it in powder form (mixed into smoothies) and gummy form (yes, they exist, and theyre *way* better than youd think)
This observation suggests a possible relationship with the body's adjustment period to the medication, though this pattern has not been formally studied
Most oral medications like Metformin show effects within days, but A1C reflects a 3-month average, so you won't see the full result in your blood test until then
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