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The GLP-1 Dominance Hypothesis Some researchers believe GLP-1 agonism drives most of the weight loss benefit, with GIP adding a modest boost

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While this is the case for most new medicines, its particularly important for those that work on several hormone pathways simultaneously

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Switching to an alternative (non glp-1) anti obesity medication The Approach Switching to a non GLP-1 anti obesity medication means replacing the GLP-1 with another approved weight loss medicine to help maintain weight loss