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Danuglipron (dosed twice daily) and orforglipron (once daily) continue in clinical trials, while the clinical development of lotiglipron (once daily) was recently stopped due to elevated transaminase liver enzymes

Plaintiffs argue that these practices included targeting children, teenagers, and other vulnerable populations while downplaying or concealing associated health risks

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Some people experience injection site reactions, small red bumps or mild itching at the injection location, that were not present at lower doses

Variants with a low allele frequency detected in genomic DNA affect the accuracy of mutation detection in cell-free DNA by next-generation sequencing