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This research was funded by the US Department of Veterans Affairs (to Z.A.A.)

When to reach out to your Care Team: If diarrhea lasts more than a day with three or more watery stools If you experience mild to moderate abdominal pain Seek immediate medical care if diarrhea is severe, persistent, or accompanied by dehydration symptoms like dizziness, confusion, or very low urine output

For semaglutide users, this translates to a practical benefit

With lunch: calcium (500 to 600mg for bone protection during rapid weight loss)

Whilst the primary mechanisms of GLP-1 drugs are well established, some people report changes in their taste perception and food preferences

Increased heart rate: A resting heart rate that suddenly feels fast or pounding should be reported to your provider