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60% of patients report insufficient nutritional guidance, affecting treatment efficacy

With the potential change in coverage, the out-of-pocket costs can be $12,000 a year or more to take these medications

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The FDA is in a public comment period - closing June 29, 2026 - on a proposal to formally exclude semaglutide and tirzepatide from the 503B Bulk Drug Substances List, a move that would permanently close large-scale compounding pathways for these active ingredients even in a future shortage