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Although MSG has proven its value as an enhancer of flavor and popular food additive, several studies have indicated possible toxic effects on the induction of metabolic changes, which can lead to major disturbances including obesity, hepatic damages, CNS (central nervous system), and reproductive disorders

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And again, you may experience some side effects, especially right after changing dose

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[Lessons from macrophagic myofasciitis: towards definition of a vaccine adjuvant-related syndrome]