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CLEV CLIN J MED 70(5):S4 Kamruzzaman HM, Hoq MO (2016) A review on ethnomedicinal, phytochemical and pharmacological properties of Phyllanthus niruri

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Increased free radical production may be associated with impaired Nitric Oxide bioavailability

In the research discussion it is emphasised that a pulsatile signal tends to preserve the natural regulation of the axis rather than continuously flooding the system