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We hypothesized that daily GH injections given in the evening could disrupt sleep both by inhibiting GHRH secretion, and due to the discomfort and psychological distress associated with the injection and local reactions

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It works by mimicking the action of the naturally occurring hormone GLP-1, which regulates appetite, slows gastric emptying, and enhances insulin secretion

4.22 times higher risk of bowel obstruction, whereby food is prevented from passing through the small or large intestine, resulting in symptoms like cramping, bloating, nausea and vomiting