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acknowledges support by the Czech Science Foundation (GA CR) grant 21-11563M and by the European Unions Horizon Europe program (ERC, TerpenCode, 101170268)

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The education level was classified into three categories as previously described [26, 27]: less than high school, high school or equivalent, and some college or above

Store GHK-Cu after reconstitution in the main body of the refrigerator, not the door

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the lysate was clarified by centrifugation at 15,000 nx g for 15 min, protein concentrations were determined using the BCA total protein assay (Pierce), and then appropriate volumes of the lysates were diluted with 2x reducing Laemmli buffer and heated for ten min at 95 C