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According to NICE guidance (NG28), GLP-1 receptor agonists like Ozempic are typically considered when triple therapy is ineffective, not tolerated or contraindicated, with specific BMI and clinical criteria

It is also synthesized in the brainstem and acts as a neuromodulator within key regions involved in reward processing, stress regulation, and executive function

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Anlogos GLP-1 El estudio revel una incidencia de cncer muy similar en ambos grupos: 5.76 casos por cada 1000 personas-ao para la ciruga baritrica y 5.64 casos por cada 1000 personas-ao para el tratamiento con anlogos GLP-1

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You can read the abstract of this article at Triple-Hormone-Receptor Agonist Retatrutide for Obesity A Phase 2 Trial PubMed (nih.gov)