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Giving patients more realistic expectations of their potential for weight loss could save time, frustration and money spent learning whether a drug works

The Problem With GLP-1 Agonists Among the most concerning claims are reports of gastroparesis, a debilitating condition characterized by stomach paralysis, which can lead to chronic nausea, vomiting, diarrhea, bowel blockages, dangerous malnutrition, and other health issues

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Using these agents, body weight reductions between 10-25% have been demonstrated in phase 3 randomised placebo-controlled trials in people with obesity, with or without T2DM, with associated improvements in cardiometabolic risk factors