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Some of the most common include an upset stomach, nausea, and headaches

However, these drugs are associated with a wide array of side effects, and some say alternatives are needed

The smaller final step from 8mg to 12mg (a 50% increase rather than a 100% doubling) reflects the finding that GI tolerability improves at higher doses once the body has already adapted to substantial receptor activation

2 References 1 Weiss, Jessica B., et al

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