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ROS determination Hydrogen peroxide (H 2 O 2 ) levels were determined according to Alexieva et al

PMID: 8698545

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Additionally, metformin has been utilized for alleviating OA symptoms through various mechanisms, including anti-inflammation, activation of autophagy, inhibition of osteoclast activation, and regulation of chondrocyte aging 21,22,23,24

MetS and its components do not yet have specific therapy recommendations

L-cysteine can be provided efficiently with N-Acetylcysteine (NAC)